For more than 20 years, many cytologic techniques have been developed for endometrial sampling such as Gravlee jet aspirator, Isaacs cell sampler, Vabra aspirator, Pipelle, etc, But none of the techniques received general acceptance as a
replacement for
dilatation and curettage. Hence dilatation and curettage is still used to evaluate women at high risk for endometrial cancer and infertility, to manage abnormal uterine bleeding and to follow women of hormone replacement therapy. But biopsy
methods
produce enough pain to lower patient's acceptance. Z-sampler is a new simple plastic endometrial suction curette that provides a histologic diagnosis like Pippelle. This study compared the clinical usability of the Z-sampler to that of
endometrial
biopsy by dilatation and curettage.
The Z-sampler obtained sufficient tissues for histologic diagnosis in 45 cases(45/50, 90.0%), it was lower than that of endometrial biopsy(49/50, 98.0%). But the accuracy of tissue diagnosis was almost equal to that of endometrial biopsy. In
addition.
Z-sampler caused less pain(94.1%) and the duration of this procedure was shorter than that of endometrial biopsy by dilatation and curettage.
These results suggest that the Z-sampler may be efficient technique in endometrial tissue diagnosis like dilatation and curettage and it has greater patient acceptability due to less pain, less bleeding and shorter duration of procedure.
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